Issue |
Genet. Sel. Evol.
Volume 34, Number 6, November-December 2002
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Page(s) | 705 - 728 | |
DOI | https://doi.org/10.1051/gse:2002026 |
DOI: 10.1051/gse:2002026
Detection of quantitative trait loci for carcass composition traits in pigs
Denis Milana, Jean-Pierre Bidanelb, Nathalie Iannuccellia, Juliette Riqueta, Yves Amiguesc, Joseph Gruandd, Pascale Le Royb, Christine Renarde and Claude Chevaletaa Laboratoire de génétique cellulaire, Institut national de la recherche agronomique, 31326 Castanet-Tolosan Cedex, France
b Station de génétique quantitative et appliquée, Institut national de la recherche agronomique, 78352 Jouy-en-Josas Cedex, France
c LABOGENA, Institut national de la recherche agronomique, 78352 Jouy-en-Josas Cedex, France
d Station expérimentale de sélection porcine, Institut national de la recherche agronomique, 86480 Rouillé, France
e Laboratoire de radiobiologie et d'étude du génome, Institut national de la recherche agronomique, 78352 Jouy-en-Josas Cedex, France
(Received 9 January 2002; accepted 9 April 2002)
Abstract
A quantitative trait locus (QTL) analysis of carcass composition data
from a three-generation experimental cross between Meishan (MS) and
Large White (LW) pig breeds is presented. A total of 488 F2 males
issued from six F1 boars and 23 F1 sows, the progeny of six LW boars
and six MS sows, were slaughtered at approximately 80 kg live weight and
were submitted to a standardised cutting of the carcass. Fifteen traits,
i.e. dressing percentage, loin, ham, shoulder, belly, backfat,
leaf fat, feet and head weights, two backfat thickness and one muscle
depth measurements, ham + loin and back + leaf fat percentages and
estimated carcass lean content were analysed. Animals were typed for a
total of 137 markers covering the entire porcine genome. Analyses were
performed using a line-cross (LC) regression method where founder
lines were assumed to be fixed for different QTL alleles and a
half/full sib (HFS) maximum likelihood method where allele
substitution effects were estimated within each half-/full-sib
family. Additional analyses were performed to search for multiple
linked QTL and imprinting effects. Significant gene effects were
evidenced for both leanness and fatness traits in the telomeric
regions of SSC 1q and SSC 2p, on SSC 4, SSC 7 and SSC X. Additional
significant QTL were identified for ham weight on SSC 5, for head
weight on SSC 1 and SSC 7, for feet weight on SSC 7 and for dressing
percentage on SSC X. LW alleles were associated with a higher lean
content and a lower fat content of the carcass, except for the fatness
trait on SSC 7. Suggestive evidence of linked QTL on SSC 7 and of
imprinting effects on SSC 6, SSC 7, SSC 9 and SSC 17 were also
obtained.
Key words: pig / gene mapping / quantitative trait locus / carcass composition
Correspondence and reprints: Denis Milan,
e-mail: milan@toulouse.inra.fr; Jean-Pierre Bidanel,
e-mail: bidanel@dga.jouy.inra.fr
© INRA, EDP Sciences 2002