Genet. Sel. Evol.
Volume 38, Number 2, March-April 2006
|Page(s)||221 - 229|
|Published online||24 February 2006|
A note on QTL detecting for censored traitsYixin Fang
Department of Statistics, Columbia University, New York, NY 10027, USA
(Received 9 August 2005; accepted 6 October 2005 ; published online 24 February 2006)
Abstract - Most existing statistical methods for mapping quantitative trait loci (QTL) assume that the phenotype follows a normal distribution and that it is fully observed. However, some phenotypes have skewed distributions and may be censored. This note proposes a simple and efficient approach to QTL detecting for censored traits with the Cox PH model without estimating the baseline hazard function which is "nuisance".
Key words: QTL detecting / censored trait / interval mapping
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© INRA, EDP Sciences 2006