Free Access
| Issue |
Genet. Sel. Evol.
Volume 38, Number 2, March-April 2006
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|---|---|---|
| Page(s) | 221 - 229 | |
| DOI | https://doi.org/10.1051/gse:2005037 | |
| Published online | 24 February 2006 | |
Genet. Sel. Evol. 38 (2006) 221-229
DOI: 10.1051/gse:2005037
Department of Statistics, Columbia University, New York, NY 10027, USA
(Received 9 August 2005; accepted 6 October 2005 ; published online 24 February 2006)
Key words: QTL detecting / censored trait / interval mapping
Correspondence and reprints: yf2113@columbia.edu
© INRA, EDP Sciences 2006
DOI: 10.1051/gse:2005037
A note on QTL detecting for censored traits
Yixin FangDepartment of Statistics, Columbia University, New York, NY 10027, USA
(Received 9 August 2005; accepted 6 October 2005 ; published online 24 February 2006)
Abstract - Most existing statistical methods for mapping quantitative trait loci (QTL) assume that the phenotype follows a normal distribution and that it is fully observed. However, some phenotypes have skewed distributions and may be censored. This note proposes a simple and efficient approach to QTL detecting for censored traits with the Cox PH model without estimating the baseline hazard function which is "nuisance".
Key words: QTL detecting / censored trait / interval mapping
Correspondence and reprints: yf2113@columbia.edu
© INRA, EDP Sciences 2006