Genet. Sel. Evol. 38 (2006) 147-165
DOI: 10.1051/gse:2005033

Optimization of a crossing system using mate selection

Yongjun Li^{a, b}, Julius H.J. van der Werf^a and Brian P. Kinghorn<sup>a, c

a</sup>  School of Rural Science and Agriculture, University of New England, Armidale NSW 2351, Australia
^b  Institute of Animal Science, Jilin Agricultural University, Changchun 130118, P.R. China
^c  Sygen Chair of Genetic Information Systems, the Institute of Genetic and Bioinformatics, University of New England, Armidale, NSW 2351, Australia

(Received 4 May 2005; accepted 21 October 2005; published online 24 February 2006)

Abstract - A simple model based on one single identified quantitative trait locus (QTL) in a two-way crossing system was used to demonstrate the power of mate selection algorithms as a natural means of opportunistic line development for optimization of crossbreeding programs over multiple generations. Mate selection automatically invokes divergent selection in two parental lines for an over-dominant QTL and increased frequency of the favorable allele toward fixation in the sire-line for a fully-dominant QTL. It was concluded that an optimal strategy of line development could be found by mate selection algorithms for a given set of parameters such as genetic model of QTL, breeding objective and initial frequency of the favorable allele in the base populations, etc. The same framework could be used in other scenarios, such as programs involving crossing to exploit breed effects and heterosis. In contrast to classical index selection, this approach to mate selection can optimize long-term responses.

Key words: quantitative trait locus / optimal utilization / two-way crossing system / mate selection

Correspondence and reprints: Yongjun.Li@inw.agrl.ethz.ch

© INRA, EDP Sciences 2006