Issue |
Genet. Sel. Evol.
Volume 38, Number 4, July-August 2006
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|
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Page(s) | 431 - 444 | |
DOI | https://doi.org/10.1051/gse:2006013 | |
Published online | 23 June 2006 |
DOI: 10.1051/gse:2006013
OLA-DRB1 microsatellite variants are associated with ovine growth and reproduction traits
Hermann Geldermann, Manzoor R. Mir, Andreas W. Kuss and Heinz BartenschlagerDepartment of Animal Breeding and Biotechnology, University of Hohenheim, D-70593 Stuttgart, Germany
(Received 22 March 2005; accepted 8 February 2006; published online 23 June 2006)
Abstract - The DRB1 intron 2 (GT)(GA)
microsatellite was genotyped in
experimental flocks of seven Merinoland rams and 249 ewes as well as their
offspring (381 lambs) from consecutive lambings. A total of 16 DRB1 alleles were
detected, ranging between 353 and 857 bp. In comparison with carriers of
other alleles, the ewes carrying the predominant 411 bp allele had higher
values of all the recorded fertility traits. For ewes carrying the 394 and
857 bp alleles, the birth weight of lambs was about 400 g higher as compared
to the residual group of ewes. The observed associations could be due to
differences in disease resistance, cell recognition or tissue
differentiation between carriers of various MHC haplotypes which can in turn
affect individual fertility and growth performance.
Key words: DRB1 / microsatellites / growth / reproduction / sheep
Correspondence and reprints: Geldermann.tzunihoh@t-online.de
© INRA, EDP Sciences 2006