Free Access
Genet. Sel. Evol.
Volume 35, Number 5, September-October 2003
Page(s) 573 - 580


  1. Altschul S.F., Madden T.L., Schäffer A.A., Zhang J., Zhang Z., Miller W., Lipman D.J., Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Res. 25 (1997) 3389-3402.
  2. Aritomi M., Kunishima N., Okamoto T., Kuroki R., Ota Y., Morikawa K., Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme, Nature 401 (1999) 713-717.
  3. Bravo J., Staunton D., Heath J.K., Jones E.Y., Crystal structure of a cytokine-binding region of gp130, EMBO J. 17 (1998) 1665-1674.
  4. Buchanan F.C., Fitzsimmons C.J., Van Kessel A.G., Thue T.D., Winkelman-Sim D.C., Schmutz S.M., Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels, Genet. Sel. Evol. 34 (2002) 105-116.
  5. Doyon C., Drouin G., Trudeau V.L., Moon T.W., Molecular Evolution of Leptin, Gen. Comp. Endocrinol. 124 (2001) 188-198.
  6. Friedman J.M., Halaas J.L., Leptin and the regulation of body weight in mammals, Nature 395 (1998) 763-770.
  7. Haegeman A., Van Zeveren A., Peelman L.J., New mutation in exon 2 of the bovine leptin gene, Anim. Genet. 31 (2000) 79.
  8. Isse N., Ogawa Y., Tamura N., Masuzaki H., Mori K., Okazaki T., Satoh N., Shigemoto M., Yoshimasa Y., Nishi S., Hosoda K., Inazawa J., Nakao K., Structural organisation and chromosomal assignment of the human obese gene, J. Biol. Chem. 270 (1995) 27728-27733.
  9. Jiang Z.-H., Gibson J.P., Genetic polymorphisms in the leptin gene and their association with fatness in four pig breeds, Mamm. Gen. 10 (1999) 191-193.
  10. Karvonen M.K., Pesonen U., Heinonen P., Laakso M., Rissanen A., Naukkarinen H., Valve R., Uusitupa M.I.J., Koulu M., Identification of new sequence variants in the leptin gene, J. Clin. Endocrinol. Metab. 83 (1998) 3239-3242.
  11. Konfortov B.A., Licence V.E., Miller J.R., Re-sequencing of DNA from a diverse panel of cattle reveals a high level of polymorphism in both intron and exon, Mamm. Genome 10 (1999) 1142-1145.
  12. Maffei M., Stoffel M., Barone M., Moon B., Dammerman M., Ravussin E., Bogardus C., Ludwig D.S., Flier J.S., Talley M., Absence of mutations in the human OB gene in obese/diabetic subjects, Diabetes 45 (1996) 679-682.
  13. Montague C.T., Farooqi I.S., Whitehead J.P., Soos M.A., Rau H., Wareham N.J., Sewter C.P., Digby J.E., Mohammed S.N., Hurst J.A., Cheetham C.H., Earley A.R., Barnett A.H., Prins J.B., O'Rahilly S., Congenital leptin deficiency is associated with severe early-onset obesity in humans, Nature 387 (1997) 903-908.
  14. Park J.P., Shared synteny of human chromosome 17 loci in Canids, Cytogenet. Cell Genet. (1996) 133-137.
  15. Patterson D., Companion animal medicine in the age of medical genetics, J. Vet. Intern. Med. 14 (2000) 1-9.
  16. Sasaki N., Shibata H., Honjoh T., Kimura K., Saito M., Ohishi I., cDNA cloning of feline leptin and its mRNA expression in adipose tissue, J. Vet. Med. Sci. 63 (2001) 1115-1120.
  17. Stratil A., Peelman L., Van Poucke M., Cepica S., A HinfI PCR-RFLP at the porcine leptin (LEP), Anim. Genet. 28 (1997) 371-372.
  18. Strobel A., Issad T., Camoin L., Ozata M., Strosberg A.D., A leptin missence mutation associated with hypogonadism and morbid obesity, Nat. Genet. 18 (1998) 213-215.
  19. Tatusova T.A., Madden T.L., BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences, FEMS Microbiol. Lett. 177 (1999) 187-188.
  20. Wayne R.K., Ostrander E.A., Origin, genetic diversity, and genome structure of the domestic dog, BioEssays 21 (1999) 247-257.
  21. Wayne R.K., Vila C., Phylogeny and Origin of the Domestic Dog, in: Ruvinsky A., Sampson J. (Eds.), The Genetics of the Dog, CAB International, Wallingford and New York, 2001, pp. 1-13.
  22. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J., Positional cloning of the mouse obese gene and its human homologue, Nature 372 (1994) 425-431.
  23. Zhang F., Basinski M.B., Beals J.M., Briggs S.L., Churgay L.M., Clawson D.K., DiMarchi R.D., Furman T.C., Hale J.E., Hsiung H.M., Schoner B.E., Smith D.P., Zhang X.Y., Wery J.-P., Schevitz R.W., Crystal structure of the obese protein leptin-E100, Nature 387 (1997) 206-209.


Copyright INRA, EDP Sciences