Issue |
Genet. Sel. Evol.
Volume 35, Number 4, July-August 2003
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|
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Page(s) | 369 - 383 | |
DOI | https://doi.org/10.1051/gse:2003029 |
DOI: 10.1051/gse:2003029
Pedigree and marker information requirements to monitor genetic variability
Roswitha Baumung and Johann SölknerDepartment of Livestock Sciences, University of Agricultural Sciences, Gregor Mendel-Str. 33, 1180 Vienna, Austria
(Received 22 April 2002; accepted 15 January 2003)
Abstract
There are several measures available to describe the genetic
variability of populations. The average inbreeding coefficient of a
population based on pedigree information is a frequently chosen
option. Due to the developments in molecular genetics it is also
possible to calculate inbreeding coefficients based on genetic marker
information. A simulation study was carried out involving ten sires
and 50 dams. The animals were mated over a period of 20 discrete
generations. The population size was kept constant. Different
situations with regard to the level of polymorphism and initial allele
frequencies and mating scheme (random mating, avoidance of full sib
mating, avoidance of full sib and half sib mating) were
considered. Pedigree inbreeding coefficients of the last generation
using full pedigree or 10, 5 and 2 generations of the pedigree were
calculated. Marker inbreeding coefficients based on different sets of
microsatellite loci were also investigated. Under random mating,
pedigree-inbreeding coefficients are clearly more closely related to
true autozygosity (i.e., the actual proportion of loci with
alleles identical by descent) than marker-inbreeding coefficients. If
mating is not random, the demands on the quality and quantity of
pedigree records increase. Greater attention must be paid to the
correct parentage of the animals.
Key words: autozygosity / inbreeding / microsatellite / quality of pedigree
Correspondence and reprints: Roswitha Baumung
e-mail: baumung@boku.ac.at
© INRA, EDP Sciences 2003